Especialistas

1. Dra. Jane Cook
2. Dr. Jagdev M Sharma

Dra. Jane Cook

Estudos no Reino Unido: Licenciatura em Microbiologia e Doutorado da Universidade de Bristol Membro do Colégio Real de Patologistas Currículo: A Dra. Jane Cook está envolvida a muitos anos no estudo da patogênese e epidemiologia das doenças virais das aves, particularmente a Bronquite Infecciosa (BI), as infecções por Adenovírus (Incluindo EDS-76) e o Pnemovírus Aviário.  Trabalhou na pesquisa e desenvolvimento de vacinas aviárias até sua aposentadoria, no ano 2000.  Desde a sua aposentadoria, a Dra. Cook se mantém relacionada ao âmbito das doenças aviárias como consultora de diferentes organizações, ministrando palestras, escrevendo capítulos de livros e revisando artigos.  Entre outras atividades, ela também é editora da revista Avian Pathology.

Publicações selecionadas:

McDougall, J.S. & Cook, J.K.A. (1986)
Turkey rhinotracheitis: preliminary investigations. Veterinary Record, 118, 206-207.

Cook, J.K.A. & Ellis, M.M. (1990)
Attenuation of turkey rhinotracheitis virus by alternative passage in embryonated chicken eggs and tracheal organ cultures. Avian Pathology, 19, 181-185.

Cook, J.K.A., Ellis, M.M. & Huggins, M.B. (1991)
The pathogenesis of turkey rhinotracheitis virus in turkey poults inoculated with the virus alone or together with two strains of bacteria. Avian Pathology, 20, 155-166.

Cook, J.K.A., Kinloch, S. & Ellis, M.M. (1993)
In vitro and in vivo studies in chickens and turkeys on strains of turkey rhinotracheitis virus isolated from the two species.  Avian Pathology, 22, 157-170.

Cook, J.K.A., Jones, B.V., Ellis, M.M., Li Jing. & Cavanagh, D. (1993)
Antigenic differentiation of strains of turkey rhinotracheitis virus using monoclonal antibodies. Avian Pathology, 22, 257-273.

Cook, J.K.A., Huggins, M.B., Woods, M.A., Orbell, S.J. & Mockett, A.P. A. (1995)
Protection provided by a commercially available vaccine against different strains of turkey rhinotracheitis virus. Veterinary Record, 136, 392-393.

Cook, J.K.A., Orthel, F., Orbell, S., Woods, M.A. & Huggins, M.B. (1996)
An experimental turkey rhinotracheitis (TRT) infection in breeding turkeys and the prevention of its clinical effects using live-attenuated and inactivated TRT vaccines. Avian Pathology, 25, 231-243.

Cook, J.K.A., Huggins, M.B., Orbell, S.J. & Senne, D. A. (1999)
Preliminary antigenic characterization of an avian pneumovirus isolated from commercial turkeys in Colorado, USA. Avian Pathology, 28, 607-617.

Cook, J. K. A., Chesher, J., Orthel, F., Woods, M. A., Orbell, S. J., Baxendale, W. & Huggins, M. B. (2000)
Avian pneumovirus infection of laying hens: experimental studies. Avian Pathology, 29, 545-556.

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Dr Jagdev M Sharma

Carreira profisional O campos de pesquisa do Dr. Sharma abrangem a imunologia aviaria, a patogênese viral, a imunosupresão e o controle das doenças causantes  e a vacinação in-ovo.

Publicações recentes

Sharma, J. M. Marek's Disease.
OIE Mannal of Standards for Diagnositc Tests and Vaccines. World Organization for Animal Health. Fifth Edition Vol.II 2005. pp 833-841.

Bublot, M and J. M. Sharma. Marek’s Disease Vaccination.
Monograph on Marek’s Disease. IAH, Compton, UK. 2004

Sharma, J.M.
The avian immune system and genetic basis of disease resistance. Diseases of Poultry. Saif, M et al., eds. Iowa State University Press. 2006 (In press).

Schijns, V., J.M. Sharma and Tarpey, I.
Practical aspects of vaccination. Avian Immunology. Davison, F et al., eds. Elsavier. 2006 (In press)

Khatri, M and J.M. Sharma.
Modulation of macrophages by infectious bursal disease virus. Special Edition, CGR, 2006 (In press)

Rautenschlein, S., H.-Y. Yeh, and J. M. Sharma.
The role of T cells in protection by an inactivated infectious bursal disease virus vaccine. Vet. Immunolo. Immunopathol. 89: 159. 2002.

Rautenschlein, S., H.-Y. Yeh, M. Njenga, and J. M. Sharma.
Role of intrabursal T cells in infectious bursal disease virus (IBDV) infection: T cells promote viral clearance but delay follicular recovery. Arch. Virol. 147:285-304. 2002.

Chary, P., S. Rautenschlein, M. K. Njenga, and J. M. Sharma.
Pathogenic and immunosuppressive effects of avian pneumovirus in turkeys. Avian Dis. 46:153-161. 2002.

Rautenschlein, S., A. M. Sheikh, D. P. Patnayak, R. L. Miller, J. M. Sharma, and S. M. Goyal.
Effect of an immunomodulator on the efficacy of an attenuated vaccine against avian pneumovirus in turkeys. Avian Dis. 46:555-561, 2002.

Chary, P., S. Rautenschlein, and J. M. Sharma.
Reduced efficacy of hemorrhagic enteritis virus vaccine in turkeys exposed to avian pneumovirus. Avian Dis. 46:353-359. 2002.

Sharma, J. M., Y. Zhang, D. Jensen, S. Rautenschlein, and H.-Y. Yeh.
A field trial in commercial broilers with a multivalent in ovo vaccine that protects against Marek’s disease, infectious bursal disease, Newcastle disease and fowl pox. Avian Dis. 46:613-622, 2002.

Yeh, H.-Y., S. Rautenschlein, and J .M. Sharma.
Protective immunity against infectious bursal disease virus in chickens in the absence of virus-specific antibodies. Veterinary Immunol. Immunopathol., 89:149-158. 2002.

Rautenschlein, S., H.-Y. Yeh, and J. M. Sharma.
Comparative immunopathogenesis of mild, intermediate and virulent strains of classical IBDV. Avian Dis., 47:66-78. 2003.

Zhang, Y. and J. M. Sharma.
Immunologic tolerance in chickens hatching from eggs injected in ovo with cell-associated turkey herpesvirus (HVT). Developmental Comp Immunology, Dev. Comp. Immunol. 27:431-438. 2003. 2003.

St. Hill, C.A, R.F. Silva and J.M. Sharma.
Detection and localization of avian alphaherpesviruses in embryonic tissues following in ovo exposure. Virus Res. 100:243-248. 2004.

Munir, S., J.M. Sharma and V. Kapur.
Transcropitional response of avian cells to infection with Newcastle disease virus. Virus Research 107:103-8. 2004

Chary, P, M.K. Njenga and J.M. Sharma.
Protection by recombinant viral proteins against a respiratory challenge with virulent avian metapneumovirus. Veterinary Immunology and Immunopathology. 108:427-432. 2005.

Palmquist, J.M., M. Khatri, Ra Mi Cha, B. Goddeeris, B. Walcheck and J.M. Sharma.
In vivo infection of chicken macrophages by virulent infectious bursal disease virus: Effects of infection on macrophage function. Viral Immunol. 2006 19:305-15. 2006

Khatri, M, J.M. Palmquist, Ra Mi Cha, and J.M. Sharma.
Infection and activation of bursal macrophages by virulent infectious bursal disease virus. Virus Res 113:44-50. 2005.

Khatri, M and J.M. Sharma.
Infectious bursal disease virus infection induces macrophage activation via p38 MAPK and NF-kB Pathways. Virus Res. 118:70-77. 2006.

Khatri, M and J.M. Sharma.
Infectious Bursal Disease Virus Grown in Chicken Macrophage Cell line has Altered Tropism for Non-permissive Chicken Embryo Fibroblast Cells. Submitted. 2006.

Khatri, M and J.M. Sharma.
Activation of neonatal lymphoid cells following in ovo exposure to infectious bursal disease virus. Submitted 2006.

Ra Mi Cha, Mahesh Khatri and Jagdev M. Sharma.
B Cell Infiltration in the Respiratory Mucosa of Turkeys Exposed to Avian Metapneumovirus. Submitted 2006.

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